Trekking in Nepal need not be considered risky affair as far as your health is concerned. But very little medical care along the trail is available, so make sure you are physically fit and healthy before departing. In case of serious illness or injury, you'll be promptly evacuated to Kathmandu, which is the best remedy. Helicopter rescue services could cost as much as us$ 1000.00 per hour and it normally takes about 2-3 hours for rescue flights in Everest or Annapurna area. Please be informed that the helicopter evacuation costs of the trekkers are charged in full to the concerned clients.

Take care of yourself along the trail by ensuring that water is boiled. Diarrhea and headaches can be the curse for trekkers. So, bring appropriate medication and use them with caution. Sunburn can also be a problem at altitude, a barrier cream will protect your skin and good sunglasses are also necessary. Blisters are another problem for the trekker and adequate supplies of band-aids are advisable.

Often known, as Acute Mountain Sickness (AMS) is particularly an important medical consideration while trekking in Nepal. Altitude sickness means the effect of altitude on those who ascend too rapidly to elevation above 3500 m.
The initial symptoms of AMS are as following:-
Nausea, vomiting, Loss of appetite, Insomnia / Sleeplessness, Persistent headache, Dizziness, confusion, Disorientation, drunken gait, Weakness, fatigue, lassitude, heavy legs, Slight swelling of hands and face, Breathlessness and breathing irregularity, Reduced urine output.

These symptoms are to be taken seriously. The only cure for the altitude sickness is to descend to lower elevations immediately and it has no other cure or substitute. Acclimatization by ascending to no more than 300 to 500 meters per day above 3500 meters and the proper amount of rest are the best methods for prevention of AMS.

So far, only few trekkers have minor effects from the altitude.It is strongly recommended that the guests with known heart, lunges or blood diseases should consult their doctor before taking a trekking trip that goes to over 4000 meter. Drink 4 liter of water minimum a day, don't exhaust yourself so much and breathe deep and take rest more than usual.